OpenTox is an FP7 funded research project, whose goal is to develop an interoperable predictive toxicology framework which may be used as an enabling platform for the creation of predictive toxicology applications.
The goal is to expand OpenTox as a community project enabling additional expert and user participants to be involved in developments in as timely a manner as possible. To this end, the OpenTox mission is to carry out developments in an open and transparent manner, and to open up discussions and development to the global community at large, who may either participate in developments or provide user perspectives. Cooperation on data standards, data integration, ontologies, integration of algorithm predictions from different methods, and testing and validation all have significant collaboration opportunities and benefits for the community. For more information about OpenTox, please visit
http://www.opentox.org/
OpenTox Workshop - Development of Predictive Toxicology Applications
On the 19th September we will hold a one day OpenTox pre-conference workshop on the Development of Predictive Toxicology Applications, which will take place ahead of the official opening of the 18th European Symposium on QSAR, 19-24 September, Rhodes, Greece. The workshop will be held at the Rodos Palace Hotel, Rhodes, Greece. There is no registration fee to participate in this workshop but places will be limited. If you want to register to the workshop and the EuroQSAR Symposium please click
here Workshop Goals
This workshop will provide detailed expert guidance on the use of the OpenTox Framework for the building of predictive toxicology applications. Developers will obtain insight on the use of OpenTox interfaces, ontologies and web services for the building of new applications and for the incorporatation of their software as web services compliant with OpenTox and other industry and regulatory standards into the OpenTox Framework. Users will learn about the current capabilities of OpenTox as an interoperable, extensible platform for the flexible development, deployment and use of in silico applications in predictive toxicology. Use cases covered will include data management, model building, prediction, validation and reporting with particular attention given to REACH regulatory requirements.
Draft Program
09.30 Introduction and Overview, Barry Hardy (Douglas Connect)
10.00 Framework Design, Christoph Helma (in silico toxicology)
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Design considerations
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Architecture
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Components
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Extensibility
10.30 Application Programming Interfaces, Nina Jeliaskova (Ideaconsult)
11.00 Coffee Break
11.30 Ontologies, Romualdo Benigni (Istituto Superiore di Sanit?)
12.00 Data Management and Integration, Nina Jeliaskova (Ideaconsult)
12.30 Algorithms, Stefan Kramer (Technical University of Munich)
13.00 Lunch
14.00 Validation, Haralambos Saramveis (National Technical University of Athens)
14.30 REACH reporting, Andreas Karwath (University of Freiburg)
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Requirements of REACH reporting
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Reporting Formats supported within OpenTox
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REACH Use Case reporting Example
15.00 Developing Applications, led by OpenTox community researchers and developers
16.00 ToxPredict Application and Case Study, led by OpenTox community researchers and developers
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Design of Application to predict toxicity
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How the Application services work together
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Application Use Case Examples
16.30 ToxCreate Application and Case Study, led by OpenTox community researchers and developers
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Design of Application to create and validate predictive toxicity models
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How the Application services work together
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Application Use Case Examples
17.00 Reception with food and drinks
Please join us for what should be an interesting and enjoyable day!
For questions related to the program, please contact Barry Hardy
